منابع مشابه
Scleroderma: From Therapeutic Nihilism to Therapeutic Optimism
Several types of inflammatory cells infiltrate the affected tissue. Different subsets of “T” lymphocyte may be observed in different affected organs in various stages of SSc. CD4 lymphocytes are increased in the affected skin, whereas CD8 lymphocytes are found more commonly in bronchoalveolar lavage of patients who have scleroderma-related interstitial lung disease (ILD). Several autoantibodies...
متن کاملNonadherence, clinical inertia, or therapeutic inertia?
in which certain therapies have adequate, even overwhelming if not unequivocal, evidence of effectiveness.5 Clinical inertia occurs, for example, when the patient fails to attain a biomarker goal (e.g., blood pressure less than 140/90 millimeters of mercury [mm Hg]) due at least in part to failure to intensify pharmacotherapy through upward dosing and/or addition of drugs to the therapeutic reg...
متن کاملAtherosclerotic renal artery stenosis, the oculostenotic reflex, and therapeutic nihilism.
Fifteen years ago, Topol and Nissen1 described the oculostenotic reflex as an “irresistible temptation ... to perform angioplasty on any significant residual stenosis,” highlighting a widely held misperception that an angiographically severe stenosis must cause ischemia and that revascularization results in clinical benefit. Although quantitative angiography improves the accuracy of stenosis se...
متن کاملEmphysema: time to say farewell to therapeutic nihilism
It is an interesting time for the management of emphysema. In this condition, destruction of lung parenchyma associated with reduced elastic recoil and dynamic airways closure produce gas trapping and increased operating lung volumes, leading to breathlessness and exercise limitation. It has historically been defined as an irreversible process, which has led to a degree of therapeutic nihilism....
متن کاملNihilism, Relativism, and Literary Theory
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ژورنال
عنوان ژورنال: Canadian Journal of Diabetes
سال: 2014
ISSN: 1499-2671
DOI: 10.1016/j.jcjd.2014.08.003